Lecture time

January 8, 2026 9:00-12:00

Lecture location

Li Haoyu , professor at the School of Instrument Science and Engineering, Harbin Institute of Technology, and director of the Institute of Advanced Optoelectronic Imaging Technology, Harbin Institute of Technology. He will be selected as a national outstanding youth in 2022 and selected as a major talent project of the Ministry of Education in 2024. Research directions include super-resolution fluorescence microscopy, biomedical photonics and advanced optoelectronic instruments. In recent years, he has led the research team to publish more than 60 papers in high-level journals such as Nature Biotechnology (2022), Nature Photonics (September 2023 cover article), Nature Methods (2024), Nature Communications (2022, 2023). Authorized 3 international PCT invention patents and 15 Chinese invention patents. Co-founded Guangzhou Super Vision Biotechnology Co., Ltd. and launched scientific research-grade super-resolution microscopes HIS-SIM (released in 2021) and Cell Xpanse (released in 2025), which have been mass-produced. Its results have been selected into the top ten developments in China's optics twice (2022, 2024) and the top ten socially influential events in China's optics three times (2021, 2023, 2024). He presides over projects of the National Natural Science Foundation of China for Youth, Outstanding Young Scholars, Instrument Special Projects, and National Key R&D Plan Projects.

The emergence of super-resolution imaging technology marks a breakthrough in the optical diffraction limit in the imaging field, and has also greatly promoted the development of the biomedical field. Using super-resolution technology, biologists can conduct precise quantitative statistics and intuitive visual analysis of subcellular structures within cells. However, super-resolution technology often requires complex acquisition equipment and specific imaging controls, and has low temporal resolution and insufficient imaging throughput, which limits the wide application of super-resolution imaging in biomedicine. In view of the limitations of the imaging field of view currently faced, we propose a new generation of high-throughput three-dimensional dynamic super-resolution imaging, which effectively improves the spatiotemporal resolution of optical microscope instruments and achieves super-resolution imaging with the highest resolution (60 nanometers), the fastest speed (564 frames/second), and the longest imaging time (1 hour) in living cells. During the imaging process, super-resolution images with 120 nm resolution and 2.4 billion pixels covering a millimeter-level field of view, including more than 2,000 cells, were recorded, providing new scientific imaging tools and instruments for biomedical research.