Lecture time

October 23, 2025 10:00-11:30

Lecture location

Conference Room 302, Building 1, Jinfeng Laboratory

Lecture Topic 1: Parasite-Mediated Alteration of Behavior and Biomolecular Dynamics in a Mouse Model

Introduction to the speaker

Kevin SW Tan , currently associate professor, department head and dean’s chair professor in the Department of Microbiology and Immunology at the National University of Singapore, and also serves as the dean of the Graduate School of Yonglu Lin Medical College. His interest in parasites began while a graduate student at the National University of Singapore and further developed while doing postdoctoral research at The Rockefeller University in New York. After receiving tenure in 2011, he devoted more time to academic research and administrative management, while continuing to pursue scientific research. Professor Tan's research focuses on uncovering parasite suicide mechanisms and using this knowledge to develop antiparasitic drugs. He is also concerned about the issue of drug resistance, and his team has developed new drug screening methods to break through resistance. Recently, the team has focused on studying the role of single-celled eukaryotes (SCEs) in the host microbiome, hoping to accelerate the discovery of new treatments for parasitic diseases through these studies.

讲座题目二：DUSP4 regulates the function of anti-tumor CD8+ T cells in colorectal cancer and improves therapeutic performance of CAR-T cells

Introduction to the speaker

Zhang Yongliang , PhD, received his PhD from the National University of Singapore (NUS) in 2002. He completed postdoctoral research in the Department of Immunology at the University of Washington and the University of Texas MD Anderson Cancer Center. In 2009, he joined the Department of Microbiology and Immunology, Wing Lok Lim School of Medicine, National University of Singapore as an assistant professor and was promoted to tenured associate professor in 2017. His research focuses on elucidating the regulatory functions of key cell signaling molecules (including dual-specificity phosphatases DUSPs and interferon regulatory factor 3IRF3) in immunity and cancer. The main current and future research direction is to develop new therapies by targeting these molecules to improve patient prognosis.

Lecture summary

This forum invited Professor Kevin SW TAN, Director of the Department of Microbiology and Immunology of the National University of Singapore, and Professor Zhang Yongliang, Chairman of the Translational Research Immunology Project, to share their latest research results and have in-depth exchanges with professors and researchers from Jinfeng Laboratory, aiming to promote international exchanges and cooperation in the field of immunology and promote the in-depth development of translational medical research.

Everyone is welcome to actively participate