Lecture preview | modeling targeting and glioblastoma: from mouse to human

Release time:2024-08-30

 

introduction to the keynote speakers

professor liu haikun, director of the department of molecular neurogenetics at the german cancer research center, distinguished professor at the institute of immunochemistry, shanghaitech university, and has received multiple awards and funding, including the embo young scientist program (the only chinese winner in 15 years), dkfz international scientist award and european research council erc consolidator fund, etc.

 

lecture summary

focusing on the core concept of precision cancer medicine, professor liu haikun's team used independently established human brain cancer mouse models to study the molecular mechanisms of neural stem cells (nscs) and brain tumor stem cells (btscs) in the occurrence of brain cancer, revealing tumor basic developmental principles of growth. these findings provide new insights into understanding cancer development, tumor heterogeneity, and glioblastoma (gbm) treatment, and provide insights into further studies of tumor initiation, genetic evolution, and preclinical target validation in primary tumor models. support. through these studies, we can excavate key molecules and cells related to tumor occurrence and development, reveal important mechanisms of tumor progression, discover molecular markers related to early and accurate diagnosis of brain cancer, and screen out tumor microenvironment and heterogeneity-specific markers. precise diagnosis and treatment targets provide effective solutions for personalized prevention and treatment of brain cancer.

 

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