academic frontier | preview of the 18th lecture

lecture title

"designed peptides against eag2-kvβ2 potassium channel target the interaction between cancer cells and neurons to treat glioblastoma"

A designer peptide against the EAG2-Kvβ2 potassium channel targets the interaction of cancer cells and neurons to treat glioblastoma

lecture time

january 30, 2024 (tuesday)

10:00-12:30

lecture location

conference room 805, building 1, jinfeng laboratory

keynote speaker

professor huang xi

introduction to the keynote speakers

huang xi, chief scientist of cancer biophysics in canada, senior researcher in the department of developmental and stem cell biology at the hospital for sick children in toronto, senior researcher at the arthur and sonia labatt brain tumor research center, and tenured associate professor in the department of molecular genetics at the university of toronto.

lecture summary

although extensive research has revealed the genetic and biochemical mechanisms of tumorigenesis, little is known about the mechanisms by which mechanical and electrical signals regulate malignancy.

professor huang xi's team focuses on the role and mechanism of ion channels in tumors, using multidisciplinary methods such as bioinformatics, drosophila and mouse genetics, xenograft modeling, high-resolution dynamic in vivo imaging, electrophysiology and bioengineering. conduct systematic research to elucidate multiple key mechanisms in the occurrence and evolution of brain glioma and medulloblastoma, and develop targeted treatment strategies.

Report content：A designer peptide against the EAG2-Kvβ2 potassium channel targets the interaction of cancer cells and neurons to treat glioblastoma.

While extensive research has informed genetic and biochemical mechanisms in tumorigenesis, how mechanical and electrical signaling regulates cancer is much less known.

Professor Huang Xi's team focuses on the role and mechanism of ion channels in tumors, using multi-disciplinary approaches in bioinformatics, Drosophila and mouse genetics, xenograft modeling, high resolution dynamic live imaging, electrophysiology, and bioengineering, conducting systematic studies to elucidate multiple key mechanisms in the genesis and evolution of gliomas and medulloblastomas, and developing targeted therapeutic strategies. This lecture will revolve around this content.